Microsoft has unveiled its AI diagnostic tool, Microsoft AI Diagnostic Orchestrator (MAI-DxO), which utilizes multiple AI agents to analyze patient symptoms and medical history. The system is designed to function as an expert medical board, determining necessary tests and providing diagnoses.
According to research published in the journal Science, MAI-DxO demonstrated an 83% diagnostic accuracy rate in tests based on medical reports, compared to 36% for general practitioners using reference materials and 22% for those without. In emergency department scenarios, the system achieved 80% accuracy versus 47% for human doctors.
The tool is built on OpenAI's GPT-5 model. Microsoft plans to initiate clinical testing of MAI-DxO at the Beth Israel Deaconess Medical Center in Boston within the next two months to evaluate its performance in real-world settings.
MAI-DxO is a component of Microsoft's broader strategy to develop a medical superintelligence. The company is exploring five additional areas for AI integration, including clinical care coordination and treatment decision-making, as outlined in the BMJ Digital Health & AI journal.






