The University of Southern California research team has developed Lollylab, a diagnostic device shaped like a lollipop. It consists of two plastic components: a perforated top and a glass fiber channel covered in paper. The device functions as a micro-laboratory, allowing saliva to flow to a sensor upon licking.
The device is designed to detect acetaminophen, a common ingredient in pain and cold medications. Researchers chose this substance because its concentration in saliva accurately reflects blood levels. Testing requires only 0.3 milliliters of saliva, roughly six drops, and the process takes approximately one minute.
Lollylab uses laser-induced graphene electrodes to trigger chemical reactions that generate recordable electrical signals. To improve user experience, the device is coated in a peach-flavored candy shell, which helps reduce patient anxiety, particularly among children.
In a small-scale trial, six adult volunteers took acetaminophen and used the device. The system successfully detected the drug within two minutes. Participants reported that the method was more comfortable and convenient than traditional cotton swab sampling.
The technology is currently in the early experimental prototype stage. The research team plans to conduct larger human studies and aims to expand the device's capabilities to detect other drugs and biomarkers in the future.





